Calls for proposals

Paediatric Clinical Research Infrastructure Service Model (PRISM) is a European consortium aiming to strengthen the conduct of multinational paediatric research by providing infrastructure and expertise to investigator-initiated studies. Funded by Horizon-Europe (GA101292607) PRISM will select, according to a two-stage procedure, pilot paediatric clinical studies with the objective to provide a comprehensive, end-to-end support for multinational investigator-initiated studies conducted in 3 to 6 countries in Europe and Canada. Eligible projects include pragmatic comparative effectiveness trials, optimisation studies, repurposing trials or observational studies in any disease area except cancer and rare diseases. A call for applications will be launched by mid-September (prismeu.org), and letters of intent should be submitted by mid-December 2026. Short-listed projects will get support from the PRISM consortium during the design and planning of the full application. Following final assessment, selected projects will receive funding covering the cost of investigation and trial coordination, and multinational trial management services provided by the PRISM consortium.